Catalogue number: X2771B
Endoribonuclease Dicer; DICER; HERNA
|Product Type||Blocking Peptide|
This peptide is the immunogen used to make Cat # X2756P. Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. Blocking Peptide to Cat # X2756P.
See vial for concentration
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Optimal concentration should be evaluated by serial dilutions.
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Ship at ambient temperature, freeze upon arrival
Products are stable for one year from purchase when stored properly
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Safety Datasheet(s) for this product: