Degenerative Spermatocyte Homolog 1 (DEGS1)Catalogue number: X2384B
|Product Type||Blocking Peptide|
The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
Synonyms: Migration-inducing gene 15 protein, MLD, dihydroceramide desaturase, sphingolipid delta 4 desaturase, DES1, MGC5079, DEGS
Immunogen: Synthetic peptide derived from the human DEGS1 protein
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Concentration: See vial for concentration
For use with DEGS1 polyclonal antibodies (Cat. No. X2090P & X2383P).
Functional Analysis: ELISA
Positive Control: Placenta
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: Products are stable for one year from purchase when stored properly
Ship Conditions: Ship on gel ice, store at -20ºC immediately upon arrival
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
1. Cadena, D.L., et al. 'The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.; Biochemistry 36:6960-6967(1997). 2. Ternes, P., et al. 'Identification and characterization of a sphingolipid delta 4-desaturase family.; J. Biol. Chem. 277:25512-25518(2002).
Database Name: UniProt
Accession number: O15121 (Human)Q5XIF5 (Rat)O09005 (Mouse)
Species Accession: Human, Rat, Mouse
Safety Datasheet(s) for this product:
Degenerative Spermatocyte Homolog 1 (DEGS1)