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Degenerative Spermatocyte Homolog 1 (DEGS1)

Catalogue number: X2384B

IsotypeIgG
Product Type Blocking Peptide
Units50 µg
HostRabbit
Species reactivity Human
Mouse
Rat
Application Western Blot

Background
The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Synonyms: Migration-inducing gene 15 protein, MLD, dihydroceramide desaturase, sphingolipid delta 4 desaturase, DES1, MGC5079, DEGS

Source

Immunogen: Synthetic peptide derived from the human DEGS1 protein

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Concentration: See vial for concentration

Applications
For use with DEGS1 polyclonal antibodies (Cat. No. X2090P & X2383P).

Functional Analysis: ELISA

Positive Control: Placenta

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Ship Conditions: Ship on gel ice, store at -20ºC immediately upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

References
1. Cadena, D.L., et al. 'The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.; Biochemistry 36:6960-6967(1997). 2. Ternes, P., et al. 'Identification and characterization of a sphingolipid delta 4-desaturase family.; J. Biol. Chem. 277:25512-25518(2002).

Protein Reference(s)

Database Name: UniProt

Accession number: O15121 (Human) Q5XIF5 (Rat) O09005 (Mouse)

Species Accession: Human, Rat, Mouse


Safety Datasheet(s) for this product:
Sodium Azide
/wp-content/uploads/2018/07/Antibody-SDS-with-Sodium-AzideV2.pdf

Degenerative Spermatocyte Homolog 1 (DEGS1)

$121.00


Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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