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Claudin 1


Catalogue number: CLA001

Units1 ml
HostRabbit
Application IHC(C
P)
Background
The antibody is well suited for the detection of Claudin-1 in tissue slices. Claudin 1-8 are a family of transmembrane proteins, which are associated with tight junctions. They are responsible for the contacts between cells. They form a molecular network inhibiting the leakage of ions and water. Tight junctions are numerous on the luminal side of epithelia and the composition of Claudins are different in different tissues. Claudin-1 (22 kDa).

Positive Control
Skin or Mamma-Ca

Pre-Treatment
Formalin-fixed tissue should be pre-treated with citrate buffer pH 6 (Art. No. DE000) 10-20 min at 100°C, cooling down for 20 min until RT is reached.

Immunogen
Synthetic peptide fragment of human Claudin-1, C-terminal

Purification Method
Purified antibody from rabbit serum in PBS, BSA, sodium azide*

Working Concentration
(liquid conc.) 1:10-1:50

Concentration
50 µg/ml

Incubation Time
60 min at RT or 18 hr at 2-8°C

Secondary Reagents
Anti-Rabbit IgG, biotinylated (Art. No. ZU101) in combination with Streptavidin:HRPO (Art. No. ZU054).

Product
Purified antibody from rabbit serum in PBS, BSA, sodium azide*

Applications
IHC(C, P)

Cross Reactivity
Human, monkey, dog, mouse, rat

Storage
2-8°C

References


Caution
*These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!

Safety Datasheet(s) for this product:

Claudin 1

$522.00

SKU: CLA001 Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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