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CEA, Carcinoembryonic Antigen, CD66e


Catalogue number: CD66E2-1

CloneCOL-1
IsotypeIgG2a, k
Units1 ml
HostMouse
Application IHC(C
P)
Background
CEA is frequently used as a differential marker for adenocarcinoma and mesothelioma. Carcinoembryonal Antigen (CEA) is a high molecular glycoprotein (180 kD), which is detected in foetal colon and in colorectal carcinoma. It is a component of the s. c. glycocalyx of the embryonal endodermal epithelium. In normal adult colon it is found in very small amount only. In colorectal carcinoma and metastases of intestinal carcinoma however, it is strongly exprimed. Human CEA.

Positive Control
Colon carcinoma

Pre-Treatment
Improvement of staining with Unmasking Fluid G (Art. No. DE007) or Unmasking Fluid C (Art. No. DE000)

Immunogen
Colon carcinoma extract from human tissue

Purification Method
Purified antibody in PBS pH 7.3, contains BSA and sodium azide (0,09%)

Working Concentration
(liquid conc.)

Concentration
50 µg/ml

Incubation Time
60 min at RT

Secondary Reagents
We recommend the use of BIOLOGO's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005).

Product
Purified antibody in PBS pH 7.3, contains BSA and sodium azide (0,09%)

Applications
IHC(C, P)

Cross Reactivity
Human

Storage
2-8°C

References
1. Sheahan K., O'Brien M.J., Burke B., Dervan P.A., O'Keane J.C., Gottlieb L.S. et al. (1990) Differential reactivities of carcinoembryonic antigen (CEA) and CEA-related monoclonal and polyclonal antibodies in common epithelial malignancies. Am. J. Clin. Pathol. 94; 157-164. . 2. Ghosh A.K., Gatter K.C., Dunnill M.S., Mason D.Y. (1987) Immunohistochemical staining of reactive Mesothelium, mesothelioma, and Lung carcinoma with a panel of monoclonal antibodies. J. Clin. Pathol. 40; 19-25. 3. Nap M., Hammarström M.-L., Börmer O., Hammarström S., Wagener C., Handt S., et al. (1992) Cancer Res. 52; 23-39

Caution
*These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!

Safety Datasheet(s) for this product:

CEA, Carcinoembryonic Antigen, CD66e

$348.00

SKU: CD66E2-1 Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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