CD57, NK Cells
Catalogue number: CD57-1
|Product Type||Monoclonal Antibody|
|Application||IHC (cryostat and paraffin sections)|
CD57 (NHK-1) is a glycoprotein with an oligosaccharide antigen determinant, which is localized especially on NK-cells, but also on subsets of T- and B-cells. T-cells expriming CD57 are upregulated in patients with HIV infection and after transplantation. The antigen is also exprimed by neuronal tissues and most neuroendocrine cells. human CD57, a 110 kDa membrane protein of human lymphocytes.
Brain, adrenal medulla
No pre-treatment necessary
Preparation of a HSB-2 T-cell line
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. BIOLOGO Art .No. PU002.
(liquid conc.) 1:10-1:100
60 min at RT
As secondary reagents we recommend the use of biotinylated anti-mouse IgM antibody (Art. No. BA-2020) in combination with streptavidin conjugates or ABC systems.
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.5% BSA and 0.09 % sodium azide**. The volume is sufficient for at least 100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. BIOLOGO Art .No. PU002.
1. Toru Abo, et al. (1984) A differentiation antigen of human NK and K cells, identified by a monoclonal antibody (NHK-1) J. Immunol. 127: 1024-1029.
*These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
Safety Datasheet(s) for this product:
CD57, NK Cells