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CD57, NK Cells

Catalogue number: CD57-1

CloneNK-1
IsotypeIgM
Product Type Monoclonal Antibody
Units1 ml
HostMouse
Species reactivity Human
Application IHC (cryostat and paraffin sections)
IHC(C
Immunohistochemistry (frozen & paraffin)
Immunohistochemistry (frozen)
Immunohistochemistry (paraffin)
P)

Background
CD57 (NHK-1) is a glycoprotein with an oligosaccharide antigen determinant, which is localized especially on NK-cells, but also on subsets of T- and B-cells. T-cells expriming CD57 are upregulated in patients with HIV infection and after transplantation. The antigen is also exprimed by neuronal tissues and most neuroendocrine cells. human CD57, a 110 kDa membrane protein of human lymphocytes.

Source

Immunogen: Preparation of a HSB-2 T-cell line

Product
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.5% BSA and 0.09 % sodium azide**. The volume is sufficient for at least 100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. BIOLOGO Art .No. PU002.

Purification Method: Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. BIOLOGO Art .No. PU002.

Secondary Reagents: As secondary reagents we recommend the use of biotinylated anti-mouse IgM antibody (Art. No. BA-2020) in combination with streptavidin conjugates or ABC systems.

Specificity

Species Reactivity: Human

Applications
IHC(C, P)

Incubation Time: 60 min at RT

Working Concentration: (liquid conc.) 1:10-1:100

Pre-Treatment: No pre-treatment necessary

Positive Control: Brain, adrenal medulla

Storage
2-8°C

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.

References
1. Toru Abo, et al. (1984) A differentiation antigen of human NK and K cells, identified by a monoclonal antibody (NHK-1) J. Immunol. 127: 1024-1029.


Safety Datasheet(s) for this product:
EA_Sodium Azide
/wp-content/uploads/SDS/Antibody SDS with Sodium AzideV2.pdf

CD57, NK Cells

$564.00

SKU: CD57-1 Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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