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CD282 (TLR2), human


Catalogue number: CD282-100

CloneTL2.1
IsotypeIgG2a
Units100 µg
HostMouse
Application FACS
Flow Cytometry
IHC(C
Immunoprecipitation
Background
This antibody is well suited to detect CD282 on peripheral blood cells an in tissues. Clone TL2.1 blocks TLR2 function. For functional studies removal of sodium azide is required! Antibody TL2.1 detects human Toll-Like Receptor 2 (TLR2) a 90kDa type 1 transmembrane protein, which primarily is exprimed by peripheral blood monocytes. TLR2, designed CD282, reacts with a number of bacterial cell wall components and initiates innate immune response in co-operation with MD-2. Human toll-like receptor 2 (TLR2), 90kDa transmembrane protein.

Positive Control
Tonsil (IHC), monocytes (FACS)

Immunogen
CHO-TLR2 cells

Purification Method
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**.

Working Concentration
(liquid conc.) 1-5 µg/ml

Concentration
100 µg/ml

Incubation Time
60 min at RT or 18 hr at 2-8°C

Secondary Reagents
We recommend the use of anti-mouse-IgG:FITC (e.g. art. no. FI-2000) or anti-mouse-IgG:RPE (e.g. art. no. EI-2000).

Product
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**.

Applications
FACS, IHC(C), Immunoprecipitation

Cross Reactivity
Human, Cynomolgus monkey, Rhesus monkey, Marmoset monkey

Storage
2-8°C

References
1. Lien, E. et al. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J. Biol. Chem. 274: 33419 - 25. 2. Flo, T. H. et al. (2001) Differential expression of toll-like receptor 2 in human cells. J. Leukoc. Biol. 69: 474 - 81.

Caution
*These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!

Safety Datasheet(s) for this product:

CD282 (TLR2), human

$743.00

SKU: CD282-100 Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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