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CD204, Macrophage Scavenger Receptor

Catalogue number: CD204-1

CloneSRA-E5
IsotypeIgG1
Product Type Primary Antibodies
Units50 µg
HostMouse
Species reactivity Human
Application IHC(C, P), WB

Background
The macrophage scavenger receptor (MSR-A) has been identified in the search for a receptor molecule responsible for the deposition of cholesterol in atherosclerosis by receptor-mediated uptake of LDL. MSR-A has a broad spectrum for ligand binding: oxidized LDL, acetylated LDL, advanced glycation end products (AGE), polyribonucleotides such as poly-G and poly-I, and bacterial surface lipids, lipopolysaccharides, and lipoteichoic acid. MSR-A, CD204, a 72 kDa glycoprotein from histiocytic macrophages.

Source

Immunogen: Recombinant human protein type I SR-A

Product

Secondary Reagents: As secondary system in immunohistochemistry we recommend our universal staining kits DAB and AEC (DA005 and AE005), the staining kit mouse IgG (rat absorbed, Item No. DA007)

Applications

Working Concentration: (liquid conc.) 2 μg / ml

Pre-Treatment: Formaldehyde-fixed tissue must be subjected to antigen unmasking, 10 min citrate buffer 0.01 M, pH 2.0, alternatively, glycol-based demasking solution G may be used (DE007).

Positive Control: Human Liver

Storage
-20°C

Caution
This is a research reagent for in vitro studies. It is not intended for clinical diagnosis. Liability for improper use is excluded by the manufacturer.

References
1.Takeya M., Tomokiyo R., Jinnouchi K., Sakaguchi H., et al: Macrophage Scavenger Receptors: Structure, Function and Tissue Distribution: Acta Histochem. Cytochem. 32 (1): 47 to 51.1999
2. Tomokiyo R., Jinnouchi K., Honda M., Wada Y., Hanada N., Hiraoka T., Suzuki H., Kodama T., Takahashi K., Takeya M .: Production, characterization, and interspecies reactivities of A macrophage scavenger receptor: Atherosclerosis, 2001
3.Takeya M., Tomokiyo R., Jinnouchi K. Honda M. et al: CD204: Macrophage scavenger receptor, a new differentiation marker for macrophages: part 9 Myeloid Cells, New CD Antigens, Leucocyte Typing Ⅶ, Oxford Univ. Press, 2001

Protein Reference(s)

Database Name: UniProt

Accession number: P21757


CD204, Macrophage Scavenger Receptor

$1,081.00

SKU: CD204-1 Categories: ,

Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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