Print Friendly, PDF & Email


Beta-Defensin-2 (HBD-2/MBD-2) control peptide


Catalogue number: DEF02-P

Units100 µg
Application Control peptide
Control peptide for DEF02-A and DEF02-S antibodies
Background
Control peptide for antibodies DEF02-S and DEF02-A Human defensins are Cys-rich antimicrobial peptides which specifically react against Gram-negative bacteria. Originally defensins were isolated from hemolysates, but they can also be found on the cell surface of epithelia of the urogenital tract, lung, and trachea. In leukocytes defensins are stored in granules being released into phagolysosomes for the destruction of incorporated microorganisms. Amino acid sequences of alpha-defensins 1-4 (HNP1-4) and beta-Defensins 1-4 (HBD1-4) are known. Beta-defensin-1 and beta-defensin-2 share 34% amino acid sequence homology. Mixture of synthetic peptides (14 AA near N-terminus of the mature HBD-2, 14 AA near N-terminus of the mature rat ß-Defensin-2, and 17 AA near N-terminus of the mature mouse ß-Defensin-2.

Purification Method
Synthetic peptide lyophilized from PBS pH 7.5 at 1 mg/ml

Working Concentration
(lyophilisate)

Product
Synthetic peptide lyophilized from PBS pH 7.5 at 1 mg/ml

Applications
Control peptide for DEF02-A and DEF02-S antibodies

Storage
-20'°C'

References
1. Harder J., Bartels J., Christophers E., and J.-M. Schröder (1997) Antibacterial peptide specific for Gram-negative Bacteria / also effective for Candida albicans. Nature 387; 861ff 2. Hiratsuka T., Nakazato M., Date Y., Ashitani J., Minematsu T, Chino N., and S. Matsukura (1998) Biochem. Biophys. Res. Comm. (Pharmacol.) 249; 943 ff

Caution
These products are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.

Beta-Defensin-2 (HBD-2/MBD-2) control peptide

$348.00

SKU: DEF02-P Categories: ,