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Sheep anti bcl-2


Catalogue number: A105P

IsotypeIgG
Product Type Polyclonal Antibody
Units250 µg
HostSheep
Species reactivity Dog
Human
Rat
Application Immunofluorescense
Immunoprecipitation
Western Blot

Background
Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter.

Synonyms: hbcl2, sheep anti human bcl 2, bcl-2

Source

Immunogen: Full length recombinant bcl-2 protein

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

Applications
Applications: Western Blots at 1:5,000, Immunoprecipitation – Empirical, Immunofluorescence 1:5000.

Functional Analysis: Western Blotting

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Ship Conditions: room temperature

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

References
1. Chida, Y., et al. 'The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice.' Gut 2005, 54, 994-1002 (Product specific)

Protein Reference(s)

Database Name: UniProt

Accession number: P10415


Safety Datasheet(s) for this product:
Sodium Azide
/wp-content/uploads/2018/07/Antibody-SDS-with-Sodium-AzideV2.pdf

Sheep anti bcl-2

$254.00


Brand

Contact us

Exalpha Biologicals, Inc.
2 Shaker Road, Unit B101
Shirley, MA 01464
Phone: 978-425-1370
Email: info@exalpha.com

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