Mouse anti Rat Adrenergic Receptor
Catalogue number: X1630M
|Product Type||Monoclonal Antibody|
The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.
Immunogen: Antibody raised to synthetic peptide internal sequence corresponding to the third intracellular loop of rat alpha 2b adrenergic receptor.
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
Antibody detects alpha2B Adrenergic Receptors (1-5 µg/ml) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.
Functional Analysis: Western Blotting
Positive Control: MDCK cells transfected with rat alpha2B adrenergic receptors.
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: Products are stable for one year from purchase when stored properly
Ship Conditions: Ship at ambient temperature, freeze upon arrival
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
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Database Name: UniProt
Accession number: P19328
Species Accession: Human
Safety Datasheet(s) for this product:
Mouse anti Rat Adrenergic Receptor