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Addicsin, Mouse (-GTRAP3-18)


Catalogue number: ADD001

Units25 µg
HostRabbit
Application IC
IF
IHC
Immunocytochemistry
Immunohistochemistry
WB
Western Blotting
Background
Addicsin (also named GTRAP3-18) was identified as a novel gene upregulated in mouse amygdala with morphine tolerant and dependent state (Ref.1,2). On the other hand, GTRAP3-18 is a newly identified protein of its rat homolog, which encodes a putative modulator of neural glutamate-transporter EAAC1. Addicsin is involved in regulating glutamate content in brain and it might be a key molecule of neuroplasticity and the neuropathology of addiction of drug, dementia, epilepsy, etc. Mouse Addicsin (GTRAP3-18).

Positive Control
Mouse brain (ddY strain)

Immunogen
Partial peptide of mouse addicsin

Purification Method
Affinity chromatography purified antibody in PBS with Block Ace as stabilizer and 0.1% Proclin as bacteriostat

Working Concentration
(liquid conc.) WB 1-5 µg/ml, IHC 0,5-2 µg/ml

Concentration
250 µg/ml

Secondary Reagents
Anti-Rabbit IgG conjugates

Product
Affinity chromatography purified antibody in PBS with Block Ace as stabilizer and 0.1% Proclin as bacteriostat

Applications
IC, IF, IHC, WB

Cross Reactivity
Mouse

Storage
-20°C

References
1. Hata T, Furukawa T, Sunamura M, Egawa S, Motoi F, Ohmura N, Marumoto T, Saya H, Horii A. (2005) RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells. Cancer Res. 65(7):2899-905. 2. Saori Akiduki , Tomoyo Ochiishi , Mitsushi J. Ikemoto (2007) Neural localization of addicsin in mouse brain. Neurosci Lett. 2007 Oct 22;426(3):149-54. 3. Akiduki S, Ikemoto MJ. (2008) Modulation of the neural glutamate transporter EAAC1 by the addicsin-interacting protein ARL6IP1. J Biol Chem. 2008 Nov 14;283(46):31323-32.

Caution
*These antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.

Addicsin, Mouse (-GTRAP3-18)

$1,028.00

SKU: ADD001 Categories: ,