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Sheep anti Rat ADAR1 (Adenosine Deaminase Acting on RNA 1)

Catalogue number: U110P

Product Type Antigen Immunoaffinity Purified Polyclonal
Units50 µg
Species reactivity Rat
Application Western Blot

Double stranded RNA specific adenosine deaminase 1 (ADAR1 or DRADA) is an enzyme involved in the editing of mammalian messenger RNAs by the site specific conversion of adenosine to inosine. ADAR 1 is thought to play a role in the editing of transcripts encoding non-NMDA glutamate receptor subunits, the 2C subtype of serotonin receptor, as well as hepatitis delta virus antigen.

Synonyms: DRADA; double strandard RNA specific adenosine deaminase 1, ADAR1


Immunogen: GST fusion protein containing amino acid 1116-1176 of the rat DRADA coding sequence. The fusion protein was constructed in the pGEX-KG vector by inserting a fragment corresponding to nucleotides +3346 through +3525 of DRADA at the XbaI and XhoI sites in the vector.


Product Form: Affinity Purified

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Antigen Immunoaffiinity Purification

Concentration: See vial for concentration

Applications: Immunoblotting - recommended dilution of 1:1000.

Functional Analysis: Western Blotting

Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Antibodies are stable for one year from purchase if stored frozen

Ship Conditions: Room Temperature

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

1. Yang, J. -H., et al. 'Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation.' J. Biol. Chem. 2003, 278, 45833-45842 2. Wang, Q., et al. 'Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene.' J. Biol. Chem. 2004, 279, 4952-4961 3. Yang, W., et al. 'ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells.' J. Biol. Chem. 2005, 280, 3946-3953

Protein Reference(s)

Database Name: UniProt

Accession number: P55266 (Rat)

Species Accession: Rat

Safety Datasheet(s) for this product:
Sodium Azide

Sheep anti Rat ADAR1 (Adenosine Deaminase Acting on RNA 1)



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Exalpha Biologicals, Inc.
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Shirley, MA 01464
Phone: 978-425-1370