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Rabbit anti Human ADAM DEC1


Catalogue number: X2416P

Synonyms
A disintegrin and metalloproteinase domain-like protein decysin 1,ADAM-like protein decysin 1

IsotypeIgG
Product Type Polyclonal Antibody
Units100 µg
HostRabbit
Species reactivity Human
Application ELISA
Western Blot
Product Form
Unconjugated

Background
ADAMDEC1 is expressed in the immune system, by dendritic cells and macrophages. It may play an important role in the control of the immune response and during pregnancy.1 Due to the partial lack of a disintegrin domain and the total lack of a cysteine-rich domain, this protein has been placed in a novel subclass of the ADAM gene family2.

Positive Control
Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.

Immunogen
Synthetic peptide derived from the human ADAMDEC1 protein.

Purification Method
Ammonium Sulfate Precipitation

Concentration
See vial for concentration

Formulation
Provided as solution in phosphate buffered saline with 0.08% sodium azide

Functional Analysis
Western Blotting

Applications
Antibody can be used for Western blotting (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions.

Storage
Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Ship Conditions
Ship at ambient temperature, freeze upon arrival

Product Stability
Reagents are stable for the period shown on the vial label when stored properly

References
1. UniProtKB/Swiss-Prot Acession # O15204 2. Bates, E.E. et. atl., The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprtease gene cluster on chromosome 8p12. Immunogenetics. 2002 May;54(2):96-105. Epub 2002 Mar 16,

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

Safety Datasheet(s) for this product:

Sodium Azide
/wp-content/uploads/2018/07/Antibody-SDS-with-Sodium-AzideV2.pdf

Rabbit anti Human ADAM DEC1

$249.00