Exalpha Biologicals, Inc.

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Product Highlight

Mouse anti-M13 phage coat protein g8p

Antibodies recognising M13 filamentous phage coat proteins are instrumental in the selection and detection of phages expressing specific antibody fragments or peptide sequences at their surface. The monoclonal antibodies manufactured and supplied by Exalpha react with either the pIII (g3p) or pVIII (g8p) proteins of M13 filamentous bacteriophage. All antibodies are available in a purified format. The antibodies are fully validated and are suitable for a wide range of techniques including:

  • ELISA
  • Flow Cytometry
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
For more information, click here for our M13 Bacteriophage information page.

News

Two more of our excellent products have been published by PubMed:

Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis
Borazanci, E., et al., J. Gastrointest. Oncol., 8, 164-172 (2017)
Using Exalpha SPARC Antibody (Cat. No. X1867P)

Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells
Steen, N.V., et al., Am. J. Cancer Res., 7, 816-830 (2017)
Using Exalpha's FITC labeled anti PY20 Antibody (Cat. No. X1017)

Armenian Hamster anti CD27

  • Product Code: MUB0365S
  • Size: 1 ml
  • Availability: In Stock In Stock
  • Price (USD): $208

Product Code

MUB0365S		 Quantity:      

Data Sheet

Product Name

Armenian Hamster anti CD27

Size

1 ml

Price (USD)

$208

Background

Members of the tumor necrosis factor receptor (TNFR) family are emerging as important molecules impliCated in the regulation of prolifeRation, differentiation and survival of T and B lymphocytes. Among these receptors is CD27, the function of which has thus far only been studied in the Human system, where it amplifies the T cell prolifeRative response induced by TCR triggering. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for geneRation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-_B and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a pro-apoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Clone Name

LG.3A10

Host

Armenian Hamster

Isotype

IgG

Species Reactivity

Human,Mouse

Product Type

Primary Antibodies

Applications

LG.3A10 is useful for flow cytometry, immunoprecipitation and immunohistochemistry on frozen and paraffin embedded sections . Optimal antibody dilution should be determined by titration. Recommended dilution for immunohistochemistry: 1:100. In combination with LG.8A6, it is possible to develop a double determinant ELISA to detect soluble Mouse CD27.

Fields of Interest

Cell adhesion,Immunology

Product Formulation

Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.

Storage Conditions

Store at 4

References

Gravestein, L.A., Nieland, J.D., Kruisbeek, A.M. and Borst, J. Int. Immunol. 7: 551-557, 1995. Gravestein, L., van Ewijk, W., Ossendorp, F. and Borst, J. J. Exp. Med. 184: 675-685, 1996. Hendriks, J., Gravestein, L.A., Tesselaar, K., van Lier, R.A.W., Schumacher, T.N.M., and Borst, J.Nature Immunol. 1: 433-440, 2000.