Exalpha Biologicals, Inc.

Latest References

Lamari, F., et al. "Disorders of phospholipids, sphingolipids and fatty acids biosynthesis: toward a new category of inherited metabolic diseases." J. Inherit. Metab. Dis. (2012), epub ahead of print

Harkewicz, R., et al. "Essential Role of ELOVL4 Protein in Very Long Chain Fatty Acid Synthesis and Retinal Function." J. Biol. Chem. (2012), 287, 11469-11480

Rosenthal, E.A., et al. "Linkage and association of phospholipid transfer protein activity to LASS4." J. Lipid Res. (2011), 52, 1837-1846

Lu, M.H., et al. "Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice." J. Physiol. (2012), epub ahead of print

Kaamiranta, K., et al. "Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population." Neurosci. Lett. (2012), 513, 233-237

Hiyoshi, M., et al. "Adiponectin receptor 2 is negatively associated with lymph node metastasis of colorectal cancer." Oncol. Lett. (2012), 3, 756-760

Guo, L., et al. "Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers." J. Lipid Res. (2012), 53, 1327-1335

ELOVL4 and other fatty acid related products from Exalpha Biologicals

Recent identification of a novel and rapidly expanding, group of 'inborn errors of metabolism' that present with neurological and or muscular disorders of phospholipids, sphingolipids and or long chain fatty acids biosynthesis has led to an expanded interest in fatty acid metabolism as it relates to regulatory bottlenecks or targets for future treatments.

Numerous disorders (14 to date) have been identified - ranging from CNS diseases to peripheral neuropathies and cardiac disorders. "These synthesis defects of complex lipid molecules stand at the frontier between classical inborn errors of metabolism and other genetic diseases involving the metabolism of structural proteins."

Exalpha offers a wide range of products for your fatty acid metabolism research. They include:

Cat. No. Name Product Type Size
X2668PAcid Ceramidase 1Antigen Affinity Purified Polyclonal10 miniblots
X1696PAdiponectin Receptor 1Polyclonal Antibody100 µg
X1699PAdiponectin Receptor 2Polyclonal Antibody100 µg
X2383PDegenerative Spermatocyte Homolog 1Antigen Affinity Purified Polyclonal10 miniblots
X2090PDegenerative Spermatocyte Homolog 1Polyclonal Antibody100 µg
X2356PDegenerative Spermatocyte Homolog 2Antigen Affinity Purified Polyclonal10 miniblots
X2357PDegenerative Spermatocyte Homolog 2Polyclonal Antibody100 µg
X2381PELOVL4Antigen Affinity Purified Polyclonal10 miniblots
X2087PELOVL4Polyclonal Antibody100 µg
X2087PELOVL4Polyclonal Antibody100 µg
X1698PFatty Acid 2-Hydrolase (Fa2H)Polyclonal Antibody100 µg
X2310PLass1 (Cross reacts with GDF1)Antigen Affinity Purified Polyclonal10 miniblots
X2311PLass1 (Non-GDF1)Antigen Affinity Purified Polyclonal10 miniblots
X2084PLass1 (Cross reacts with GDF1)Polyclonal Antibody100 µg
X2083PLass1 (Non-GDF1)Polyclonal Antibody100 µg
X2304PLass3Antigen Affinity Purified Polyclonal10 miniblots
X2298PLass4Antigen Affinity Purified Polyclonal10 miniblots
X2300PLass4Polyclonal Antibody100 µg
X1652PLysophospatidic Acid Acetyltransferase betaAntigen Affinity Purified Polyclonal10 miniblots
X2359PSphingomyelin Phosphodiesterase 3Antigen Affinity Purified Polyclonal10 miniblots
X2360PSphingomyelin Phosphodiesterase 3Polyclonal Antibody100 µg
X2065PSphingomyelin Synthase 1 (peptide antigen)Antigen Affinity Purified Polyclonal10 miniblots
X1701PSphingomyelin Synthase 1 (peptide antigen)Polyclonal Antibody100 µg
X1702PSphingomyelin Synthase 1 (recombinant protein antigen)Polyclonal Antibody100 µg
X1631PSphingosine 1-Phosphate Lyase 1Antigen Affinity Purified Polyclonal10 miniblots