Exalpha Biologicals, Inc.

EXALPHA PRODUCT CITATIONS

BrdU Immunohistochemistry Kit (Cat. No. X1545K)

1. Sato, S., et al. "Central control of bone remodeling by neuromedin U." Nature Medicine (2007), 13, 1234-1240.

BrdU Cell Proliferation Assay Kit (Cat. No. X1327K)

1. Nanakin, A., et al. "Expression of the REG IV gene in ulcerative cells." Laboratory Investigation (2007), 87, 304-314.
2. Chang, V., et al. "Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines." Cancer Gene Therapy (2007), 14, 927-933.
3. Sekine, C., et al. "Successful Treatment of Animal Models of Rheumatoid Arthritis with Small-Molecule Cyclin-Dependent Kinase Inhibitors." J. Immunol. (2008), 180, 1954-1961.
4. Matta, H., et al. "Activation of alternative NF-κB pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1β-converting enzyme inhibitory protein (vFLIP)." Proc. Natl. Acad. Sci. (2004), 101, 9399-9404.

Ceramide Glycosyltransferase (Cat. No. X1700P)

1. D'Angelo, G., et al. "Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide." Nature (2007), 449, 62-67.

DAP12 (Cat. No. X1588P)

1. Zou, W., et al. "DAP12 Couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk." Mol. Cell. (2008) 31(3), 422-431

Lysophosphatidic Acid Receptor

1. Shida, D., et al. "Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer." Laboratory Investigation (2004), 84, 1352-1362.

Sphingosine 1-Phosphate Receptor Antibodies

1. Goparaju, S.K., et al. "The S1P2 Receptor Negatively Regulates Platelet-Derived Growth Factor-Induced Motility and Proliferation." Mol. Cell. Biol. (2005), 25, 4237-4249.

Ion Channel Antibodies

1. Burkhalter, A., et al. "Differential Expression of IA Channel Subunits Kv4.2 and Kv4.3 in Mouse Visual Cortical Neurons and Synapses." J. Neurosci. (2006), 26, 12274-12282.
2. Luo, Z.D., et al. "Upregulation of Dorsal Root Ganglion alpha 2delta Calcium Channel Subunit and Its Correlation with Allodynia in Spinal Nerve-Injured Rats." J. Neurosci. (2001), 21, 1868-1875.

M13 Antibodies

1. Sakai, Keiko et al, "Isolation and Characterization of Phage-Displayed Single Chain Antibodies Recognizing Nonreducing Terminal Mannose Residues. 1. A New Strategy for Generation of Anti-Carbohydrate Antibodies", Biochemistry, 2007, 46 (1), pp 253–262
2. Qi,Cai et al, "Phage M13KO7 detection with biosensor based on imaging ellipsometry and AFM microscopic confirmation", Virus Research, In Press, Corrected Proof, Available online 24 December 2008
3. Kelly, Kimberly A. et al, "SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration", Journal of Leukocyte Biology, Vol 81, March 2007 pp 748-756
4. Tragoolpua, Khajornsak et al.,"Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells", BMC Biotechnol. 2008; 8: 5.

Nerve Growth Factor Antibodies

1. Wild, K.D., et al. "Antibodies to Nerve Growth Factor Reverse Established Tactile Allodynia in Rodent Models of Neuropathic Pain without Tolerance." J. Pharmacol. Exp. Ther. (2007), 322, 282-287.

Chx10 Antibodies (Cat. No. X1179P & X1180P)

1. Qiu, F., et al. "A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors." J. Neurosci. (2008), 28, 3392-3403.
2. Elshatory, Y., et al. "Islet-1 Controls the Differentiation of Retinal Bipolar and Cholinergic Amacrine Cells." J. Neurosci. (2007), 27, 12707-12720.
3. Osakada, F., et al. "Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals." J. Neurosci. (2007), 27, 4210-4219.

Vasoactive Intestinal Peptide Receptor Antibodies
1. Petkov, V., et al. "Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension." J. Clin. Invest. (2003), 111, 1339-1346.

Cyclooxygenase Antibodies

1. Kaneshiro, Y., et al. "Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats." Kidney International (2006), 70, 641-646.

LEF-1/TCF Antibodies

1. Denys, H., et al. "Identification of IGFBP-6 as a significantly downregulated gene by β-catenin in desmoid tumors." Oncogene (2004), 23, 654-664
2. Aoki, M., et al. "Oncogenic transformation by β-catenin: deletion analysis and characterization of selected target genes." Oncogene (2002), 21, 6983-6991.
3. Grueneberg, D.A., et al. "A Functional Screen in Human Cells Identifies UBF2 as an RNA Polymerase II Transcription Factor That Enhances the ß-Catenin Signaling Pathway." Mol. Cell. Biol. (2003), 23, 3936-3950.
4. Li, F-Q, et al. "Lymphoid Enhancer Factor-1 Links Two Hereditary Leukemia Syndromes through Core-binding Factor {alpha} Regulation of ELA2." J. Biol. Chem. (2004), 279, 2873-2884.
5. Dorfman, D.M., et al. "Loss of Expression of the WNT/β-Catenin-Signaling Pathway Transcription Factors Lymphoid Enhancer Factor-1 (LEF-1) and T Cell Factor-1 (TCF-1) in a Subset of Peripheral T Cell Lymphomas." Am. J. Pathol. (2003), 162(5), 1539-1544
6. Yokoyama, S., et al. "Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage." Pigment Cell & Melanoma Research (2008), 21(4), 457-463.
7. Willinger, T., et al. "Human Naive CD8 T Cells Down-Regulate Expression of the WNT Pathway Transcription Factors Lymphoid Enhancer Binding Factor 1 and Transcription Factor 7 (T Cell Factor-1) following Antigen Encounter In Vitro and In Vivo." J. Immunol. (2006), 176, 1439-1446
8. Holnthoner, W., et al. " Fibroblast Growth Factor-2 Induces Lef/Tcf-dependent Transcription in Human Endothelial Cells." J. Biol. Chem. (2002), 277, 45847-45853.

PIG-3 Antibodies (Cat. No. X1155P & X1156M)

1. Marusyk, A., et al. "p53 mediates senescence-like arrest induced by chronic replicational stress." Mol. Cell. Bio. (2007), 27, 5336-5351.

Microphthalmia Antibody (Cat. No. X1405M)
1. Tshori, S., et al. "Transcription factor MITF regulates cardiac growth and hypertrophy." J. Clin. Invest. (2006), 116, 2673-2681.

Bax Antibody (Cat. No. A100M)

1. Annis, M., et al. "Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis." EMBO J. (2005), 24, 2096-2103.
2. Soucie, E.L., et al. "Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria." Mol. and Cell. Biol. (2001), 21, 4725-4736.

KSHV/HHV8 antibodies

1. Watanabe, T., et al. "Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Prolongs the Life Span of Primary Human Umbilical Vein Endothelial Cells." J. Virol. (2003), 77, 6188-6196.

Collapsin Response Mediator Protein-1 (CRMP-1) (Cat. No. X1789P & X1790P)

1. Nilsen, J., et al. "Estradiol In Vivo Regulation of Brain Mitochondrial Proteome." J. Neurosci. (2007), 27, 14069-14077.

SNAP Antibodies

1. Chae, T., et al. "The hyh mutation uncovers roles for αSnap in apical protein localization and control of neural cell fate." Nature Genetics (2004), 36, 264-270.

EBNA3A, B & C antibodies (Cat. No. F115P, F120P, F125P)

1. Anderton, E., et al. "Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma." Oncogene (2007), 27, 421-433
2. O'Nions, J., et al. "Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2." Oncogene (2003), 22, 7181-7191.
3. Jiménez-Ramírez, C., et al. "Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter." J. Virol. (2006), 80, 11200-11208.
4. Yuan, J., et al. "Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication." J. Virol. (2006), 80, 2548-2565.
5. Hong, G.K., et al. "Epstein-Barr Virus Lytic Infection Contributes to Lymphoproliferative Disease in a SCID Mouse Model." J. Virol. (2005), 79, 13993-14003.
6. Rosendorff, A., et al. "EBNA3C Coactivation with EBNA2 Requires a SUMO Homology Domain." J. Virol. (2004), 78, 367-377.
7. Maruo, S., et al. "Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth." J. Virol. (2003), 77, 10437-10447.
8. Gordadze, A.V., et al. "Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus." J. Virol. (2001), 75, 5899-5912.
9. Dalbiès-Tran, R., et al. "Amino Acids of Epstein-Barr Virus Nuclear Antigen 3A Essential for Repression of Jkappa -Mediated Transcription and Their Evolutionary Conservation." J. Virol. (2001), 75, 90-99.

Caspase-12 Antibodies (Cat. No. X1114P & X1115P)

1. Hetz, C., et al. "Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein." EMBO J. (2003), 22, 5435-5445.
2. Hetz, C., et al. "The Disulfide Isomerase Grp58 Is a Protective Factor against Prion Neurotoxicity." J. Neurosci. (2005), 25, 2793-2802.

Farnesyl Antibody (Cat. No. X1165P)

1. Clase, A.C., et al. "The Pseudorabies Virus Us2 Protein, a Virion Tegument Component, Is Prenylated in Infected Cells." J. Virol. (2003), 77, 12285-12298.

P110 antibody (Cat. No. A115M)

1. Criollo, A., et al. "Regulation of autophagy by the inositol trisphosphate receptor." Cell Death and Differentiation (2007), 14, 1029-1039.

p27 antibody (Cat. No. C155M)

1. Vella, V., et al. "Interleukin-4 stimulates papillary thyroid cancer cell survival: Implications in patients with thyroid cancer and concomitant Graves' disease." J. Clin. Endocrinol. Metab. (2004), 89, 2880-2889.

Protein Phosphatase antibodies

1. Maeda, T., et al. "Involvement of serine/threonine protein phosphatases sensitive to okadaic acid in restraint stress-induced hyperlocomotion in cocaine-sensitized mice." British Journal of Pharmacology (2006), 148, 405-412.
2. Chen, Z., et al. "Loss of Zap-70 and low molecular weight phosphotyrosine phosphatase occurs after therapy in a patient with B-chronic lymphocytic leukemia." Leukemia (2005), 19, 1503-1505.
3. Leung-Pineda, V., et al. "Phosphorylation of Chk1 by ATR Is Antagonized by a Chk1-Regulated Protein Phosphatase 2A Circuit." Mol. Cell. Biol. (2006), 26, 7529-7538.

CD56 Antibody (Cat. No. 0561)

1. Horikawa, M., et al. "Abnormal Natural Killer Cell Function in Systemic Sclerosis: Altered Cytokine Production and Defective Killing Activity." Journal of Investigative Dermatology (2005), 125, 731-737
2. Ishimoto, H., et al. "Midkine, a heparin-binding growth factor, selectively stimulates proliferation of definitive zone cells of the human fetal adrenal gland." J. Clin. Endocrinol. Metab. (2006), 91, 4050-4056.
3. Muench, M., et al. "Isolation of Definitive Zone and Chromaffin Cells Based upon Expression of CD56 (Neural Cell Adhesion Molecule) in the Human Fetal Adrenal Gland." J. Clin. Endocrinol. Metab. (2003), 88, 3921-3930.
4. Miles, L.A., et al. "Cell-Surface Actin Binds Plasminogen and Modulates Neurotransmitter Release from Catecholaminergic Cells." J. Neurosci. (2006), 26, 13017-13024.

Flow Cytometry

1. Bonetta, L. "Flow Cytomtry smaller and better." Nature Methods (2005), 2, 785-795.
2. Takebayashi, M., et al. "Blood dendritic cells are decreased in acute graft-versus-host disease." Bone Marrow Transplantation (2004), 33, 989-996.
3. Arpinati, M., et al. "Use of anti-BDCA-2 antibody for detection of dendritic cells type-2 (DC2) in allogeneic hematopoietic stem cell transplantation." Bone Marrow Transplantation (2002), 29, 887-891.
4. Kawabata, S., et al. "Induction of Th2 Cytokine Expression for p27-Specific IgA B Cell Responses after Targeted Lymph Node Immunization with Simian Immunodeficiency Virus Antigens in Rhesus Macaques." Journal of Infectious Diseases (1998), 177, 26-33.
5. Sauermann, U., et al. "Homozygosity for a Conserved Mhc Class II DQ-DRB Haplotype Is Associated with Rapid Disease Progression in Simian Immunodeficiency Virus–Infected Macaques: Results from a Prospective Study." Journal of Infectious Diseases (2000), 182, 716-724.
6. Heilmann, C., et al. "Staphylococcus aureus Fibronectin-Binding Protein (FnBP)–Mediated Adherence to Platelets, and Aggregation of Platelets Induced by FnBPA but Not by FnBPB." Journal of Infectious Diseases (2004), 190, 321-329.
7. O'Neill, E., et al. "Dynamic Evolution of the Human Immunodeficiency Virus Type 1 Pathogenic Factor, Nef." J. Virol. (2006), 80, 1311-1320.
8. Foster, J.L., et al. "Genetic and Functional Diversity of Human Immunodeficiency Virus Type 1 Subtype B Nef Primary Isolates." J. Virol. (2001) 75, 1672-1680.
9. Chakrabarti, L.A., et al. "Normal T-Cell Turnover in Sooty Mangabeys Harboring Active Simian Immunodeficiency Virus Infection." J. Virol. (2000), 74, 1209-1223.
10. Goldstein, S., et al. "Plateau Levels of Viremia Correlate with the Degree of CD4+-T-Cell Loss in Simian Immunodeficiency Virus SIVagm-Infected Pigtailed Macaques: Variable Pathogenicity of Natural SIVagm Isolates." J. Virol. (2005), 79, 5153-5162.
11. Chakrabarti, L.A., et al. "A Truncated Form of Nef Selected during Pathogenic Reversion of Simian Immunodeficiency Virus SIVmac239{Delta}nef Increases Viral Replication." J. Virol. (2003), 77, 1245-1256.
12. Chakrabarti, L.A., et al. " Properties of the Surface Envelope Glycoprotein Associated with Virulence of Simian-Human Immunodeficiency Virus SHIVSF33A Molecular Clones." J. Virol. (2002), 76, 1588-1599.
13. Cappelli, G., et al. " Human Macrophage Gamma Interferon Decreases Gene Expression but Not Replication of Mycobacterium tuberculosis: Analysis of the Host-Pathogen Reciprocal Influence on Transcription in a Comparison of Strains H37Rv and CMT97." Infect. Immun. (2001), 69, 7262-7270.
14. Luo, T., et al. "Human Immunodeficiency Virus Type 1 Nef-Induced CD4 Cell Surface Downregulation Is Inhibited by Ikarugamycin." J. Virol. (2001), 75, 2488-2492.
15. Weidmann, A., et al. "Proteolytic Cleavage of the Fusion Protein but Not Membrane Fusion Is Required for Measles Virus-Induced Immunosuppression In Vitro." J. Virol. (2000), 74, 1985-1993.
16. Anderson, S.J., et al. " The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef." J. Virol. (1994), 68, 3092-3101.

NuCycl Kits

1. Eriksson, M., et al. "Recurrent de novo point mutations in lamin A cause Hutchinson?Gilford progeria syndrome." Nature (2003), 423, 293-298.

Protein A & G Agarose gel

1. Abdullah, M., et al. "Killing of dsrA Mutants of Haemophilus ducreyi by Normal Human Serum Occurs via the Classical Complement Pathway and Is Initiated by Immunoglobulin M Binding." Infect. Immun. (2005), 73, 3431-3439.