Ceramide Kinase and Related Proteins

Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondria-mediated apoptosis. Sphingosine inhibits several protein kinases, including protein
kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.

Ceramide Kinase (Recombinant) Antibody (Cat. No. X1705P) - Antibody produced against full-length recombinant Ceramide Kinase protein.

Ceramide Kinase (Peptide) Antibody (Cat. No. X1715P) - Antibody produced against a selected peptide derived from the Ceramide Kinase protein.

Ceramide Glycosyltransferase Antibody (Cat. No. X1700P) - Antibody produced against a selected peptide derived from the Ceramide Glycosyltransferase protein, an enzyme which transfer glucose to ceramide. This enzyme is the first step in the synthesis of glycosphingolipids.